George States (Jeff Doucette) is suffering from the last stage of brain cancer and has only six months to live. In order to prevent death and gain immortality, he decides to extract the 'Nagmani' from a shape-shifting snake who can take human form, Nagin (Mallika Sherawat). He captures the nag [the male snake] so that the nagin [the female] comes after the capturer to free her lover, thus allowing him to obtain the nagmani by force. He keeps the nag in a glass box where he electrocutes him. His plan works and the nagin starts following him. On her way, she is helped by a police inspector (Irrfan Khan) and his wife (Divya Dutta), who is infertile, causing a strain in their relationship. The nagin also helps a few women who are helpless: One who is beaten mercilessly by her husband; one being raped by a man and so on. She brutally murders those men who torture women and the police inspector who is helping her find her mate takes care of the murder cases. The nagin also engages in sexual intimacy with a snake while she is in human form. Finally, she reaches George but finds her mate dead. George is wearing a suit due to which the nagin can't see him. He captures her too and tries taking the nagmani but at that moment, the police inspector arrives and helps her. Angered at the murder of her mate in the hands of George, she takes a huge form: half snake, half woman, and throws him in the same glass box where her mate was kept and electrocutes him. The ending shows George's rotten body still lying in the glass box, the police inspector and his wife finally having a child and the nagin's eggs hatching.
2012-01-24